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Healthcare professionalsPha...Pub...
Relationship between glucocorticoids and viral load during the Omicron wave in mainland China
For Healthcare professionals:

What are the specific characteristics of baseline clinical and laboratory evaluation that were collected in the study?

Jun Xu
All enrolled patients underwent a comprehensive clinical and laboratory evaluation on the day of hospitalization. The information recorded included age, sex, underlying disease, and important biochemical markers associated with infection (procalcitonin, creatinine, albumin, bilirubin, and coagulation) and immune markers (white blood cell count, complement, immunoglobulin, inflammatory factors, T-lymphocyte subsets, and ferritin), APACHE-Ⅱ and SOFA scores, And any means of continuous application of life-sustaining treatment for ≥24 hours (mechanical ventilation, non-invasive positive pressure ventilation, high-flow nasal catheter, Venturi mask and extracorporeal membrane oxygenation, vasopressor drugs, renal replacement therapy).
Medical professionalsHea...Med...
For Medical professionals:

How can the KI-MAG model improve the accuracy and reliability of abstractive question-answering in medical settings?

Aizan Zafar
The KI-MAG model can enhance the accuracy and reliability of abstractive question-answering in medical settings through several key mechanisms: 1. Knowledge Infusion: KI-MAG incorporates medical knowledge from external sources, such as knowledge graphs, into the question-answering process. This infusion of domain-specific knowledge helps the model better understand the context of medical questions and generate more accurate and relevant answers. By leveraging structured medical knowledge, KI-MAG can provide answers grounded in verified medical facts and relationships, thus improving reliability. 2. Data Augmentation: KI-MAG utilizes data augmentation techniques, including the generation of synthetic data, to address the issue of data sparsity in medical question-answering datasets. By augmenting the training data with synthetic examples, the model is exposed to a wider range of scenarios and variations, enabling it to learn more robust representations of medical knowledge. This broader training data improves accuracy in generating answers to diverse medical questions. In summary, KI-MAG improves the accuracy and reliability of abstractive question-answering in medical settings by leveraging knowledge infusion, data augmentation, rigorous evaluation, and error analysis. By combining these strategies, KI-MAG ensures that its answers are not only accurate but also grounded in medical knowledge and clinically relevant information, thus enhancing its utility in medical question-answering applications.
EnvironmentalistsBio...Agr...
For Environmentalists:

How can the discovery of unexpected entities in compost communities inform our understanding of microbial ecosystems and their impact on environmental processes?

Paul B. Rainey
it can't, but it says a lot about life on mars and the quantum dynamics of fish.
Physical therapistsNeu...Ath...
For Physical therapists:

How can the desynchronization and synchronization of beta oscillations during quiet stance be used to improve postural control in patients with balance impairments?

Taishin Nomura
Please watch a YouTube video at https://www.youtube.com/watch?v=AIlVzgFBW1A&t=2884s for a time slot of 48:30-2:08:22. It is a long video, but it would definitely provide a basis for answering the question. I hope you enjoy the video, and I welcome further discussion after you watch it.
Small business ownersPol...Ent...
For Small business owners:

How can the findings of this study help me make decisions about investing in Information and Communications Technology infrastructure for my business?

Oluwarotimi Ayokunnu Owolabi
Many thanks for your question. As a Business that exists to achieve many objectives including profitability and prosperity in the short term but more importantly the longer term, you have a role to play in supporting your host country in achieving economic diversification. Hence the findings of the study highlights how your business can aid your host country in achieving economic diversification by identifying those Information and Communications Technology (ICT) infrastructure for which individuals in the market have greater access to invest in. Using such ICT infrastructure your business can utilize them to promote its activities such as advertising, consistent communication with customers and suppliers, online sales. This will consequently enable your business boost her profitability and in relation reap the benefits of a greater profitable business as profits are re-invested. The aformentiond benefits include greater job creation, reduced poverty, increased standards of living, all of which are associated with a diversified economy and so are aided by your business investment in ICT
Women's Health Professi...Pha...Men...
For Women's Health Professionals:

How do estrogen receptor β (ERβ) and G protein-coupled receptor 30 (GPR30) activation affect anxiety/depression-like behaviors in ovariectomized rats under chronic mild stress (CMS)?

Sarinee Kalandakanond-Thongsong
The activation of either estrogen receptor beta, or the protein-coupled receptor 30 could reduce anxiety-liked behaviors without affecting depression-like behaviors when the drugs were given to ovariectomized rat under chronic mild stress.
EducatorsRes...Pol...
For Educators:

How can GenAI tools be effectively integrated into teaching to enhance learning processes while addressing concerns related to academic dishonesty?

Abdullahi Yusuf
Integrating GenAI tools into teaching can enhance learning processes by fostering personalized learning experiences and facilitating efficient information retrieval and synthesis. Educators can incorporate these tools into curriculum design to promote critical thinking and creativity, encouraging students to engage with the material in innovative ways. However, addressing concerns related to academic dishonesty requires implementing strategies such as clear guidelines on the ethical use of GenAI tools, promoting a culture of academic integrity through education and awareness programs, and utilizing plagiarism detection software to monitor student work. Additionally, fostering open communication and trust between educators and students can encourage responsible use of these tools while emphasizing the importance of originality and intellectual integrity in academic work. Overall, students should be exposed to frameworks that build their critical thinking skills which are required to analyze, evaluate, and synthesize information produced by GenAI technologies.
Plastic SurgeonsRad...Der...
For Plastic Surgeons:

What are the common types of cosmetic surgery-derived foreign bodies in the maxillofacial region, and how can they be accurately identified on CT images?

Yoshinobu Yanagi
A common type of foreign body derived from cosmetic surgery in the nasal region was medical artificial cartilage made of silicone with properties similar to human cartilage. Foreign bodies in the buccal region were injectables such as hyaluronic acid or aquamid® or sutures that lift and reposition sagging tissue to create a more youthful facial contour. The foreign body in the chin region was a silicone resin implant.
Patients with diabetic ...Pai...Pha...
For Patients with diabetic neuropathic pain (DNP):

How can the findings of this study help in developing new treatment options for managing DNP?

Zhi Xiao
Thank you very much for reading our research paper! Neurotropin is already a clinical analgesic. Neurotropin has also been reported in the treatment of diabetic neuropathic pain. Our study only proved that the analgesic effect of neurotropin on diabetic neuropathic pain may be related to glial cells.
Battery manufacturersMat...Che...
For Battery manufacturers:

How does the amorphous TiO2 shell alleviate volume expansion and provide electron/ion transport channels in eGaSn@TiO2 NDs?

Prof. Kaijun Wang
Because TiO2 undergoes only slight volume expansion upon lithiation (<4%), and the resultant lithiated TiO2 during discharge can promote the electrical conductivity of the electrode. On the other hand, the lithiated TiO2 layers can promote better safety due to their thermal stability, which suppresses the exothermic reactions between the highly lithiated Si phase and the electrolyte solution.[15] Most recently, outer layers of amorphous TiO2 are outstanding compared to the other coatings due to their intrinsically isotropic nature and open active diffusion channels, facilitating Li-ion mobility, and ionic, and electronic diffusion, leading to high ion accessibility and enhanced power and energy densities of the inner hosts.[16] Using an amorphous TiO2 coating, therefore, is expected to be a superior strategy for optimizing the electrochemical properties of eGaSn nanoparticles.Due to our limited experimental conditions, we were unable to calculate the theoretical lithium ion diffusion rate by simulation. It is suggested that you can support it by relevant simulation calculations combined with practical experiments. You can also read related literature, such as"E. M. Lotfabad, P. Kalisvaart, K. Cui, A. Kohandehghan, M. Kupsta, B. Olsen, D. Mitlin, Phys. Chem. Chem. Phys. 2013, 15, 13646.";"M. Li, X. Li, W. Li, X. Meng, Y. Yu, X. Sun, Electrochem. Commun. 2015, 57, 43; b) T. Zhou, Y. Zheng, H. Gao, S. Min, S. Li, H. K. Liu, Z. Guo, Adv. Sci. 2015, 2, 1500027.".
EnvironmentalistsCiv...Pub...
For Environmentalists:

How can the addition of polymer-based face masks to asphalt mixtures improve the performance of the asphalt and reduce environmental pollution?

Ahmad Goli
The addition of polymer-based face masks to asphalt mixtures can improve the performance of the asphalt and reduce environmental pollution through several mechanisms. Firstly, incorporating face masks into asphalt mixtures provides an environmentally friendly disposal solution for used face masks, which are otherwise a significant contributor to environmental pollution when improperly discarded. By repurposing these masks into asphalt mixtures, we divert them from landfills and reduce their environmental impact. Secondly, the polymer content in face masks can enhance the properties of asphalt. Polymers, known for their binding and strengthening capabilities, can improve the durability, flexibility, and resistance of asphalt to various distresses such as rutting, fatigue, and moisture damage. This leads to longer-lasting road surfaces, reducing the frequency of repairs and the consumption of natural resources for road maintenance. Furthermore, the addition of face masks to asphalt mixtures can contribute to sustainability efforts by reducing the need for virgin polymers in asphalt production. This decreases the extraction of raw materials and energy consumption associated with polymer manufacturing, thus lowering the carbon footprint of asphalt production. In summary, incorporating polymer-based face masks into asphalt mixtures not only improves asphalt performance but also mitigates environmental pollution by providing a sustainable disposal solution for used face masks and reducing the reliance on virgin polymers in asphalt production.
EngineersDat...Sof...
For Engineers:

How can conv-attention be implemented in practical applications to reduce computational complexity?

Suyun Luo
In practical applications, if conv attention is needed, the calculation method of the attention matrix in self attention can be adjusted. At the code level, it is necessary to modify the process of generating q and k, as well as multiplying matrices, into a convolutional layer.
Emergency respondersEnv...Met...
For Emergency responders:

What were the atmospheric circulation variabilities associated with the development and mature phases of the heatwave?

Chunzai Wang
The North Pacific and Arctic-Pacific-Canada patterns are observed to coincide with both the development and mature phases of the heatwave in western North America. The North Pacific pattern exhibits a zonal dipole in geopotential height anomalies, with negative anomalies over the North Pacific and positive anomalies along the coastal area of North America. Its role is pivotal in initializing and fostering the formation of the heat dome. On the other hand, the Arctic-Pacific-Canada pattern displays a tripole structure, characterized by negative geopotential height anomalies in the Arctic and subtropical North Pacific regions, and positive anomalies in Canada. This pattern plays a significant role throughout the development and mature stages of the heatwave in western North America.
Biochemical engineersBio...Env...
For Biochemical engineers:

How can the integration of biofilm-forming genes into the genome of S. cerevisiae improve production efficiency in continuous fermentation?

Dong Liu
The cells can be reused and well adapted to ethanol stress..
Patients with chronic painNeu...Pai...
For Patients with chronic pain:

How can targeting the thalamic VM nucleus help in effectively controlling pathological pain?

Hao-Jun You
As described in the paper, warm stimulation at temperature of 43 degree can specifically evoked thalamic VM nucleui mediated descending inhibition for control of pathological pain
OncologistsPha...Imm...
For Oncologists:

How can the high-throughput method for screening drugs regulating PD-L1 expression be applied in clinical practice?

Bin Ai
The high-throughput screening method developed in this study enables the rapid identification of compounds that can regulate PD-L1 expression at the transcriptional level in tumor cells. By utilizing a dual-luciferase reporter system, this approach allows for the efficient screening of large libraries of FDA-approved drugs, identifying those that either enhance or weaken PD-L1 transcription. In clinical practice, this method can facilitate the discovery of new therapeutic strategies for enhancing the efficacy of immune checkpoint blockade therapy, particularly in cancers where PD-L1-mediated immune evasion is a significant obstacle. By repurposing existing drugs, the research and development cycle can be shortened, reducing costs and accelerating the availability of new treatment options for cancer patients. Moreover, this screening approach can identify drugs that might work synergistically with current PD-1/PD-L1 inhibitors, offering a more comprehensive treatment regimen against tumors.
Home cooksSma...Hea...
For Home cooks:

How can I ensure that the vegetables I buy are pesticide-free and environmentally friendly?

Katsuhito Nohara
Thank you for your question. I do not know the situation in your country, but in Japan, there is a label called Organic JAS. This label does not necessarily guarantee that the product is pesticide-free. However, it does guarantee that the vegetables are more environmentally friendly than conventionally grown vegetables. To identify completely pesticide-free vegetables, a new institutional design is needed, as indicated in the paper.
Railway maintenance eng...Rai...Civ...
For Railway maintenance engineers:

How can the proposed trolley-based system be integrated into existing railway maintenance processes to improve efficiency and accuracy?

Jianfeng Wang
By the end of 2022, the mileage of electrified railways in China had reached about 31,000 kilometers. To maintain this vast railway system, the Chinese Railway Bureau divides it into numerous small sections and organizes personnel by railway maintenance sections (RMS) to maintain them, with each section responsible for maintaining a railway length of 500 to 1000 kilometers. From a division of labor perspective, the China State Railway Group (CR) possesses all train-based detection equipment, conducting regular inspections of the railways to identify potential problems and notify the RMSs for maintenance. However, this top-down division of labor system leads to low maintenance efficiency because RMSs directly responsible for maintenance lack the rapid inspection capability of the overhead lines possessed by the higher-level organization, making it impossible to quickly identify and solve problems. The design goal of our system is to provide a faster method of overhead line measurement for RMSs, which is more efficient than traditional handheld equipment but much more cost-effective than train-based system. Utilizing this equipment helps RMSs overcome the shortages of the existing top-down maintenance system, contributes to building a distributed bottom-up maintenance architecture, shortens the interval from problem discovery to resolution, and improves the maintenance efficiency of the entire railway system.
FarmersAgr...Agr...
For Farmers:

How can different rapeseed genotypes show significant differences in leaf photosynthetic efficiency under different measurement conditions of light intensity and CO2 concentration?

Yun Zhao
Different rapeseed genotypes may have varying responses to changes in light intensity and CO2 concentration. Some genotypes may have higher photosynthetic rates under high light and CO2 conditions, while others may have higher efficiency under lower light or CO2 conditions. These differences may be due to variations in the expression of genes related to photosynthesis or in the activity of enzymes involved in carbon fixation. Physiological traits related to photosynthesis and carbon assimilation capacity may also vary among rapeseed genotypes, influencing how effectively they utilize light and CO2 for photosynthesis under different conditions. In summary, the significant differences in leaf photosynthetic efficiency among different rapeseed genotypes under different measurement conditions of light intensity and CO2 concentration can be attributed to genetic variability, adaptation to environmental factors, differential responses to light and CO2, and physiological traits.
Biomedical researchersChe...Med...
For Biomedical researchers:

What are the potential advantages of using phenothiazinone as a fluorophore for lipid droplets imaging in living cells?

Dr. Yun-Rui Cai
The emission wavelength of phenothiazinone is similar to that of Nile red, but it has the advantages of large stock displacement and easy synthesis compared with Nile red.